Rheumatoid arthritis is a chronic autoimmune inflammatory disease that mainly affects the joints. It can lead to pain, stiffness, and, in advanced stages, joint deformities and loss of function. Early diagnosis and proper treatment are crucial to prevent complications and maintain quality of life.

What Is Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is an autoimmune disorder in which the immune system mistakenly attacks the body’s own tissues — primarily the synovial membrane lining the joints. This causes chronic inflammation that can damage not only the joints but also organs such as the lungs, skin, or heart.

Causes of Rheumatoid Arthritis

The exact cause is still unknown, but certain risk factors contribute to its development:

  • Genetics: Family history increases risk.
  • Environmental Factors: Exposure to cigarette smoke, infections, or harmful substances.
  • Hormonal Imbalances: RA is more common in women, suggesting hormones play a role.
  • Immune System Dysfunction: An abnormal immune response triggers joint inflammation.

Symptoms of Rheumatoid Arthritis

Symptoms vary but often include:

  • Joint pain and swelling, usually symmetrical (both hands, knees, or wrists)
  • Stiffness, especially in the morning or after inactivity
  • Chronic fatigue
  • Low-grade fever
  • Unintentional weight loss
  • Rheumatoid nodules — small lumps under the skin, often on the elbows

How Is It Diagnosed?

Diagnosis involves:

  • A detailed clinical exam
  • Blood tests: ESR, CRP, rheumatoid factor (RF), and anti-CCP antibodies
  • Imaging: X-rays, ultrasound, or MRI to check for joint damage

Treatment of Rheumatoid Arthritis

Treatment aims to control inflammation, slow disease progression, and maintain a good quality of life. Options include:

1. Medications

  • NSAIDs: Reduce pain and inflammation
  • Corticosteroids: Used for severe or acute flare-ups
  • DMARDs (Disease-Modifying Anti-Rheumatic Drugs): Such as methotrexate, to slow progression
  • Biologics: Advanced treatments that target specific immune pathways (e.g., adalimumab, etanercept)

2. Physiotherapy

Regular exercises help maintain mobility and muscle strength, preventing deformities.

3. Surgery

In advanced cases, joint replacement or other orthopedic procedures may be required.

Lifestyle and Recommendations

  • Follow an anti-inflammatory diet rich in omega-3s, vegetables, and fruits; avoid processed foods.
  • Engage in regular, gentle physical activity suitable for your condition.
  • Avoid smoking and manage stress levels.
  • Attend regular check-ups to adjust treatment as needed.

Rheumatoid Arthritis in Children — Juvenile Idiopathic Arthritis

When RA occurs in children under 16, it is called juvenile idiopathic arthritis. Pediatric care is essential, as the disease may present differently and requires tailored treatment.

Prognosis

Rheumatoid arthritis is chronic, but with modern treatments and lifestyle adjustments, many patients maintain an active, independent life. Early diagnosis and good medical follow-up are vital.

Conclusion

Rheumatoid arthritis should never be ignored. While it has no cure yet, proper management, medication, and a healthy lifestyle can slow its progression and greatly improve daily life. If you have symptoms, don’t hesitate to see your doctor.

Frequently asked questions

Which joints are most often affected?

Hands, wrists, knees, and ankles are commonly involved.

Treatment combines medications like methotrexate, biologics for severe cases, NSAIDs for pain, and physiotherapy. Surgery may be needed in advanced stages.

Through clinical exams, blood tests, and imaging scans.

An anti-inflammatory diet can help ease symptoms.

Yes, light, regular exercise helps maintain mobility.

Yes, severe RA can impact the heart, lungs, or eyes.

At least every 3–6 months, or more often if needed.

There is no cure, but treatment can control the disease and help many patients reach remission.